Title |
Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels
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Published in |
Biotechnology for Biofuels and Bioproducts, April 2013
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DOI | 10.1186/1754-6834-6-57 |
Pubmed ID | |
Authors |
Yanning Zheng, Qiang Liu, Lingling Li, Wen Qin, Jianming Yang, Haibo Zhang, Xinglin Jiang, Tao Cheng, Wei Liu, Xin Xu, Mo Xian |
Abstract |
The isopentenols, including isoprenol and prenol, are excellent alternative fuels. However, they are not compounds largely accumulated in natural organism. The need for the next generation of biofuels with better physical and chemical properties impels us to develop biosynthetic routes for the production of isoprenol and prenol from renewable sugar. In this study, we use the heterogenous mevalonate-dependent (MVA) isoprenoid pathway for the synthesis of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) intermediates, and then convert IPP and DMAPP to isoprenol and prenol, respectively. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | 1% |
Indonesia | 1 | <1% |
New Zealand | 1 | <1% |
Belgium | 1 | <1% |
United States | 1 | <1% |
Unknown | 144 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 40 | 27% |
Researcher | 23 | 15% |
Student > Master | 19 | 13% |
Student > Bachelor | 14 | 9% |
Student > Doctoral Student | 7 | 5% |
Other | 23 | 15% |
Unknown | 24 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 63 | 42% |
Biochemistry, Genetics and Molecular Biology | 30 | 20% |
Chemistry | 7 | 5% |
Engineering | 5 | 3% |
Chemical Engineering | 5 | 3% |
Other | 9 | 6% |
Unknown | 31 | 21% |