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DNMT1 genetic polymorphisms affect breast cancer risk in the central European Caucasian population

Overview of attention for article published in Clinical Epigenetics, May 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)

Mentioned by

twitter
3 tweeters
wikipedia
1 Wikipedia page

Citations

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27 Dimensions

Readers on

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38 Mendeley
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Title
DNMT1 genetic polymorphisms affect breast cancer risk in the central European Caucasian population
Published in
Clinical Epigenetics, May 2013
DOI 10.1186/1868-7083-5-7
Pubmed ID
Authors

Kathrin Kullmann, Mustafa Deryal, Mei Fang Ong, Werner Schmidt, Ulrich Mahlknecht

Abstract

DNA methylation of CpG islands within the promoter region of genes is an epigenetic modification with an important role in the development of cancer and it is typically mediated by DNA methyltransferases (DNMTs). In cancer cells, global hypomethylation of the genome as a whole and regional hypermethylation of CpG islands have been reported. Four groups of DNMTs have been identified: DNMT1, DNMT2 (TRDMT1), DNMT3A and DNMT3B. DNMT2 uses the catalytic mechanism of DNMTs, but does in fact methylate RNA. Little is known about the significance of these genes in human breast cancer. In the study presented herein, we analyzed five distinct DNMT single SNPs with regard to potential associations with breast cancer risk.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Uruguay 1 3%
Unknown 37 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 26%
Student > Ph. D. Student 7 18%
Student > Bachelor 5 13%
Researcher 4 11%
Professor > Associate Professor 4 11%
Other 5 13%
Unknown 3 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 26%
Medicine and Dentistry 9 24%
Biochemistry, Genetics and Molecular Biology 8 21%
Chemistry 3 8%
Environmental Science 1 3%
Other 0 0%
Unknown 7 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2014.
All research outputs
#5,055,046
of 18,796,975 outputs
Outputs from Clinical Epigenetics
#328
of 1,025 outputs
Outputs of similar age
#42,756
of 166,848 outputs
Outputs of similar age from Clinical Epigenetics
#1
of 1 outputs
Altmetric has tracked 18,796,975 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,025 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,848 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them