↓ Skip to main content

Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma

Overview of attention for article published in Journal of Therapeutic Ultrasound, December 2016
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
11 Dimensions

Readers on

mendeley
39 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma
Published in
Journal of Therapeutic Ultrasound, December 2016
DOI 10.1186/s40349-016-0078-3
Pubmed ID
Authors

Giovanni Borasi, Alan Nahum, Margarethus M. Paulides, Gibin Powathil, Giorgio Russo, Laura Fariselli, Debora Lamia, Roberta Cirincione, Giusi Irma Forte, Cristian Borrazzo, Barbara Caccia, Elisabetta di Castro, Silvia Pozzi, Maria Carla Gilardi

Abstract

A new transcranial focused ultrasound device has been developed that can induce hyperthermia in a large tissue volume. The purpose of this work is to investigate theoretically how glioblastoma multiforme (GBM) can be effectively treated by combining the fast hyperthermia generated by this focused ultrasound device with external beam radiotherapy. To investigate the effect of tumor growth, we have developed a mathematical description of GBM proliferation and diffusion in the context of reaction-diffusion theory. In addition, we have formulated equations describing the impact of radiotherapy and heat on GBM in the reaction-diffusion equation, including tumor regrowth by stem cells. This formulation has been used to predict the effectiveness of the combination treatment for a realistic focused ultrasound heating scenario. Our results show that patient survival could be significantly improved by this combined treatment modality. High priority should be given to experiments to validate the therapeutic benefit predicted by our model.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 23%
Student > Bachelor 6 15%
Researcher 5 13%
Other 4 10%
Professor > Associate Professor 4 10%
Other 8 21%
Unknown 3 8%
Readers by discipline Count As %
Medicine and Dentistry 9 23%
Physics and Astronomy 7 18%
Mathematics 3 8%
Engineering 3 8%
Neuroscience 2 5%
Other 6 15%
Unknown 9 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2016.
All research outputs
#4,722,843
of 8,745,512 outputs
Outputs from Journal of Therapeutic Ultrasound
#35
of 62 outputs
Outputs of similar age
#164,039
of 299,671 outputs
Outputs of similar age from Journal of Therapeutic Ultrasound
#1
of 3 outputs
Altmetric has tracked 8,745,512 research outputs across all sources so far. This one is in the 27th percentile – i.e., 27% of other outputs scored the same or lower than it.
So far Altmetric has tracked 62 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,671 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them