Title |
Evidence of effective scrapie transmission via colostrum and milk in sheep
|
---|---|
Published in |
BMC Veterinary Research, May 2013
|
DOI | 10.1186/1746-6148-9-99 |
Pubmed ID | |
Authors |
Timm Konold, S Jo Moore, Susan J Bellworthy, Linda A Terry, Leigh Thorne, Andrew Ramsay, F Javier Salguero, Marion M Simmons, Hugh A Simmons |
Abstract |
Evidence for scrapie transmission from VRQ/VRQ ewes to lambs via milk was first reported in 2008 but in that study there were concerns that lateral transmission may have contributed to the high transmission rate observed since five control lambs housed with the milk recipients also became infected. This report provides further information obtained from two follow-up studies, one where milk recipients were housed separately after milk consumption to confirm the validity of the high scrapie transmission rate via milk and the second to assess any difference in infectivity from colostrum and subsequent milk. Protein misfolding cyclic amplification (PMCA) was also used to detect prion protein in milk samples as a comparison with the infectivity data and extended to milk samples from ewes without a VRQ allele. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
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Indonesia | 1 | 2% |
Unknown | 48 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 9 | 18% |
Researcher | 9 | 18% |
Student > Bachelor | 5 | 10% |
Student > Doctoral Student | 4 | 8% |
Other | 3 | 6% |
Other | 9 | 18% |
Unknown | 10 | 20% |
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Biochemistry, Genetics and Molecular Biology | 8 | 16% |
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Medicine and Dentistry | 3 | 6% |
Other | 5 | 10% |
Unknown | 10 | 20% |