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The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice

Overview of attention for article published in Alzheimer's Research & Therapy, January 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#38 of 1,104)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
6 news outlets
blogs
4 blogs
twitter
30 tweeters
patent
2 patents
facebook
5 Facebook pages
wikipedia
1 Wikipedia page
googleplus
3 Google+ users
reddit
1 Redditor

Citations

dimensions_citation
66 Dimensions

Readers on

mendeley
113 Mendeley
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Title
The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice
Published in
Alzheimer's Research & Therapy, January 2013
DOI 10.1186/alzrt179
Pubmed ID
Authors

Marguerite Prior, Richard Dargusch, Jennifer L Ehren, Chandramouli Chiruta, David Schubert

Abstract

Despite years of research, there are no disease-modifying drugs for Alzheimer's disease (AD), a fatal, age-related neurodegenerative disorder. Screening for potential therapeutics in rodent models of AD has generally relied on testing compounds before pathology is present, thereby modeling disease prevention rather than disease modification. Furthermore, this approach to screening does not reflect the clinical presentation of AD patients which could explain the failure to translate compounds identified as beneficial in animal models to disease modifying compounds in clinical trials. Clearly a better approach to pre-clinical drug screening for AD is required.

Twitter Demographics

The data shown below were collected from the profiles of 30 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 <1%
Unknown 110 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 30 27%
Student > Master 20 18%
Student > Ph. D. Student 14 12%
Other 11 10%
Student > Bachelor 8 7%
Other 15 13%
Unknown 15 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 20%
Medicine and Dentistry 20 18%
Biochemistry, Genetics and Molecular Biology 14 12%
Pharmacology, Toxicology and Pharmaceutical Science 13 12%
Neuroscience 8 7%
Other 14 12%
Unknown 21 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 105. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2022.
All research outputs
#303,024
of 21,407,661 outputs
Outputs from Alzheimer's Research & Therapy
#38
of 1,104 outputs
Outputs of similar age
#2,120
of 173,909 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#1
of 5 outputs
Altmetric has tracked 21,407,661 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,104 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,909 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them