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The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice

Overview of attention for article published in Alzheimer's Research & Therapy, May 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
6 news outlets
blogs
4 blogs
twitter
28 X users
patent
4 patents
facebook
5 Facebook pages
wikipedia
1 Wikipedia page
googleplus
3 Google+ users
reddit
1 Redditor

Citations

dimensions_citation
78 Dimensions

Readers on

mendeley
125 Mendeley
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Title
The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice
Published in
Alzheimer's Research & Therapy, May 2013
DOI 10.1186/alzrt179
Pubmed ID
Authors

Marguerite Prior, Richard Dargusch, Jennifer L Ehren, Chandramouli Chiruta, David Schubert

Abstract

Despite years of research, there are no disease-modifying drugs for Alzheimer's disease (AD), a fatal, age-related neurodegenerative disorder. Screening for potential therapeutics in rodent models of AD has generally relied on testing compounds before pathology is present, thereby modeling disease prevention rather than disease modification. Furthermore, this approach to screening does not reflect the clinical presentation of AD patients which could explain the failure to translate compounds identified as beneficial in animal models to disease modifying compounds in clinical trials. Clearly a better approach to pre-clinical drug screening for AD is required.

X Demographics

X Demographics

The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 <1%
Unknown 122 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 30 24%
Student > Master 21 17%
Student > Ph. D. Student 14 11%
Student > Bachelor 11 9%
Other 11 9%
Other 17 14%
Unknown 21 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 18%
Medicine and Dentistry 21 17%
Biochemistry, Genetics and Molecular Biology 16 13%
Pharmacology, Toxicology and Pharmaceutical Science 15 12%
Neuroscience 8 6%
Other 15 12%
Unknown 27 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 104. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2023.
All research outputs
#410,324
of 25,619,480 outputs
Outputs from Alzheimer's Research & Therapy
#62
of 1,486 outputs
Outputs of similar age
#2,781
of 206,583 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#1
of 11 outputs
Altmetric has tracked 25,619,480 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,486 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,583 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.