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Hepatitis viruses in Ethiopia: a systematic review and meta-analysis

Overview of attention for article published in BMC Infectious Diseases, December 2016
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Title
Hepatitis viruses in Ethiopia: a systematic review and meta-analysis
Published in
BMC Infectious Diseases, December 2016
DOI 10.1186/s12879-016-2090-1
Pubmed ID
Authors

Yeshambel Belyhun, Melanie Maier, Andargachew Mulu, Ermias Diro, Uwe Gerd Liebert

Abstract

The existing seroepidemiological data on viral hepatitis in Ethiopia showed a wide variation in prevalence pattern and the clinical and public health burden have been underestimated. The aim of this systematic review and meta-analysis was to provide a clear and comprehensive estimation of viral hepatitis epidemiology and the potential clinical burdens in Ethiopia. A comprehensive literature search was carried out from five decades (1968-2015) published studies from biomedical databases; PubMed, Google scholar, Medline and Web of Science. The overall pooled prevalence of hepatitis B virus (HBV) was 7.4% (95%CI: 6.5-8.4). The pooled prevalence among subgroups showed 5.2% (95%CI: 3.7-7.4) in human immunodeficiency virus (HIV) infected individuals, 8.0% (95%CI: 5.9-10.7) in community based studies, 8.4% (95%CI: 5.4-12.7) in blood donors, 11.0% (95%CI: 7.5-15.9) in immigrants and 6.9% (95%CI: 5.6-8.5) in other groups. Among study parameters considered during meta-regression analysis, only study years were associated with a decreasing HBV prevalence rate over time. The overall pooled prevalence of anti-hepatitis C virus antibody (anti-HCV) was 3.1% (95%CI: 2.2-4.4). Unlike HBV, the anti-HCV prevalence in HIV infected individuals was higher (5.5%, 95%CI: 3.8-7.8%, p = 0.01) than the prevalence observed in the other subgroup of study population. Although relatively few data were available, hepatitis virus A (HAV), D (HDV) and E (HEV) were also circulated in Ethiopia. This review indicates that all types of viral hepatitis origins are endemic in Ethiopia. Adapting a recommended diagnostic and treatment algorithm of viral hepatitis in the routine healthcare systems and implementing prevention and control policies in the general population needs an urgent attention.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 221 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 221 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 35 16%
Lecturer 19 9%
Researcher 18 8%
Student > Postgraduate 14 6%
Student > Ph. D. Student 14 6%
Other 42 19%
Unknown 79 36%
Readers by discipline Count As %
Medicine and Dentistry 57 26%
Nursing and Health Professions 24 11%
Immunology and Microbiology 18 8%
Biochemistry, Genetics and Molecular Biology 6 3%
Agricultural and Biological Sciences 6 3%
Other 29 13%
Unknown 81 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 September 2019.
All research outputs
#19,292,491
of 23,881,329 outputs
Outputs from BMC Infectious Diseases
#5,794
of 7,931 outputs
Outputs of similar age
#315,896
of 425,227 outputs
Outputs of similar age from BMC Infectious Diseases
#135
of 195 outputs
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