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Evidence for new targets and synergistic effect of metronomic celecoxib/fluvastatin combination in pilocytic astrocytoma

Overview of attention for article published in Acta Neuropathologica Communications, May 2013
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Mentioned by

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1 tweeter

Citations

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16 Dimensions

Readers on

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36 Mendeley
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Title
Evidence for new targets and synergistic effect of metronomic celecoxib/fluvastatin combination in pilocytic astrocytoma
Published in
Acta Neuropathologica Communications, May 2013
DOI 10.1186/2051-5960-1-17
Pubmed ID
Authors

Sandy Mercurio, Laetitia Padovani, Carole Colin, Manon Carré, Aurélie Tchoghandjian, Didier Scavarda, Sally Lambert, Nathalie Baeza-Kallee, Carla Fernandez, Céline Chappé, Nicolas André, Dominique Figarella-Branger

Abstract

Pilocytic astrocytomas occur predominantly in childhood. In contrast to the posterior fossa location, hypothalamo-chiasmatic pilocytic astrocytomas display a worse prognosis often leading to multiple surgical procedures and/or several lines of chemotherapy and radiotherapy to achieve long-term control. Hypothalamo-chiasmatic pilocytic astrocytomas and cerebellar pilocytic astrocytomas have a distinctive gene signature and several differential expressed genes (ICAM1, CRK, CD36, and IQGAP1) are targets for available drugs: fluvastatin and/or celecoxib.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
France 1 3%
Belgium 1 3%
Unknown 33 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 22%
Student > Bachelor 8 22%
Student > Ph. D. Student 4 11%
Student > Doctoral Student 3 8%
Student > Master 3 8%
Other 4 11%
Unknown 6 17%
Readers by discipline Count As %
Medicine and Dentistry 16 44%
Biochemistry, Genetics and Molecular Biology 4 11%
Agricultural and Biological Sciences 3 8%
Nursing and Health Professions 2 6%
Computer Science 1 3%
Other 1 3%
Unknown 9 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2013.
All research outputs
#3,094,885
of 4,506,935 outputs
Outputs from Acta Neuropathologica Communications
#145
of 186 outputs
Outputs of similar age
#62,021
of 90,033 outputs
Outputs of similar age from Acta Neuropathologica Communications
#2
of 3 outputs
Altmetric has tracked 4,506,935 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 186 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,033 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.