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Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression

Overview of attention for article published in Epigenetics & Chromatin, February 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#6 of 612)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
6 news outlets
twitter
1 X user
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
91 Mendeley
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Title
Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression
Published in
Epigenetics & Chromatin, February 2013
DOI 10.1186/1756-8935-6-3
Pubmed ID
Authors

Adrienne Grzenda, Gwen Lomberk, Phyllis Svingen, Angela Mathison, Ezequiel Calvo, Juan Iovanna, Yuning Xiong, William Faubion, Raul Urrutia

Abstract

Histone methyltransferase enhancer of zeste homologue 2 (EZH2) forms an obligate repressive complex with suppressor of zeste 12 and embryonic ectoderm development, which is thought, along with EZH1, to be primarily responsible for mediating Polycomb-dependent gene silencing. Polycomb-mediated repression influences gene expression across the entire gamut of biological processes, including development, differentiation and cellular proliferation. Deregulation of EZH2 expression is implicated in numerous complex human diseases. To date, most EZH2-mediated function has been primarily ascribed to a single protein product of the EZH2 locus.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 90 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 24%
Student > Ph. D. Student 21 23%
Student > Doctoral Student 10 11%
Student > Bachelor 9 10%
Student > Master 8 9%
Other 11 12%
Unknown 10 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 44%
Biochemistry, Genetics and Molecular Biology 20 22%
Medicine and Dentistry 11 12%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Environmental Science 2 2%
Other 7 8%
Unknown 9 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 47. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2024.
All research outputs
#872,809
of 25,295,968 outputs
Outputs from Epigenetics & Chromatin
#6
of 612 outputs
Outputs of similar age
#5,820
of 199,250 outputs
Outputs of similar age from Epigenetics & Chromatin
#1
of 12 outputs
Altmetric has tracked 25,295,968 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 612 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,250 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.