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Identification and characterization of cancer stem cells in canine mammary tumors

Overview of attention for article published in Acta Veterinaria Scandinavica, December 2016
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Title
Identification and characterization of cancer stem cells in canine mammary tumors
Published in
Acta Veterinaria Scandinavica, December 2016
DOI 10.1186/s13028-016-0268-6
Pubmed ID
Authors

Agata Rybicka, Magdalena Król

Abstract

Cancer stem cells (CSC) represent a small subpopulation of cells in malignant tumors that possess the unique ability to self-renew, differentiate and resist chemo- and radiotherapy. These cells have been postulated to be the basis for some of the difficulties in treating cancer, and therefore, numerous approaches have been developed to specifically target and eliminate CSC in diverse types of cancer, including breast cancer. Spontaneously occurring mammary tumors in canines share clinical and molecular similarities with the human counterpart, making the dog a potentially powerful model for the study of human breast cancer and clinical trials. Studies focused on canine mammary CSC might therefore enhance our understanding of the biology and possible treatment of the disease in both dogs and humans. In this review, we discuss various approaches currently in use to isolate and characterize canine mammary CSC.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 16%
Student > Master 11 15%
Student > Bachelor 9 12%
Student > Postgraduate 5 7%
Professor > Associate Professor 5 7%
Other 14 19%
Unknown 17 23%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 25 34%
Agricultural and Biological Sciences 9 12%
Medicine and Dentistry 7 10%
Biochemistry, Genetics and Molecular Biology 4 5%
Immunology and Microbiology 2 3%
Other 7 10%
Unknown 19 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2016.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Acta Veterinaria Scandinavica
#692
of 837 outputs
Outputs of similar age
#362,799
of 422,468 outputs
Outputs of similar age from Acta Veterinaria Scandinavica
#9
of 11 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 837 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 422,468 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.