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Present status and upcoming prospects of hedgehog pathway inhibitors in small cell lung cancer therapy

Overview of attention for article published in Infectious Agents and Cancer, May 2013
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3 X users

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18 Mendeley
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Title
Present status and upcoming prospects of hedgehog pathway inhibitors in small cell lung cancer therapy
Published in
Infectious Agents and Cancer, May 2013
DOI 10.1186/1750-9378-8-17
Pubmed ID
Authors

Syed Hassan Abbas Naqvi, Syed Hassan Shiraz Naqvi, Muhammad Yasin Bandukda, Syed Mumtaz Ali Naqvi

Abstract

Lung cancer is an important etiology of malignant mortality worldwide with global statistics indicating over 1 million deaths annually. Although there have been advances in cytotoxic chemotherapy, the prognosis after treatment still remains poor. Remarkably, recent studies on the molecular level are creating the possibility to hamper lung cancer by inhibiting the hedgehog pathway. Currently, hedgehog pathway inhibitors include IWP-2, cyclopamine and aprotinin. However, Vismodegib is a new upcoming prospect which has shown positive results while undergoing clinical trials. If approved, it may lead to a novel class of anti-cancer therapy for patients seeking treatment for small cell lung cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 50%
Student > Bachelor 2 11%
Student > Ph. D. Student 2 11%
Student > Doctoral Student 1 6%
Other 1 6%
Other 0 0%
Unknown 3 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 50%
Medicine and Dentistry 3 17%
Biochemistry, Genetics and Molecular Biology 2 11%
Chemistry 1 6%
Unknown 3 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2013.
All research outputs
#13,890,585
of 22,711,242 outputs
Outputs from Infectious Agents and Cancer
#178
of 514 outputs
Outputs of similar age
#107,185
of 195,606 outputs
Outputs of similar age from Infectious Agents and Cancer
#6
of 12 outputs
Altmetric has tracked 22,711,242 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 514 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,606 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.