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A validated spectrofluorimetric method for the determination of nifuroxazide through coumarin formation using experimental design

Overview of attention for article published in BMC Chemistry, May 2013
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Title
A validated spectrofluorimetric method for the determination of nifuroxazide through coumarin formation using experimental design
Published in
BMC Chemistry, May 2013
DOI 10.1186/1752-153x-7-90
Pubmed ID
Authors

Asmaa Ahmed El-Zaher, Marianne Alphonse Mahrouse

Abstract

Nifuroxazide (NF) is an oral nitrofuran antibiotic, having a wide range of bactericidal activity against gram positive and gram negative enteropathogenic organisms. It is formulated either in single form, as intestinal antiseptic or in combination with drotaverine (DV) for the treatment of gastroenteritis accompanied with gastrointestinal spasm. Spectrofluorimetry is a convenient and sensitive technique for pharmaceutical quality control. The new proposed spectrofluorimetric method allows its determination either in single form or in binary mixture with DV. Furthermore, experimental conditions were optimized using the new approach: Experimental design, which has many advantages over the old one, one variable at a time (OVAT approach).

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Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 20%
Student > Master 5 14%
Student > Bachelor 3 9%
Lecturer 2 6%
Other 2 6%
Other 5 14%
Unknown 11 31%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 5 14%
Chemistry 5 14%
Medicine and Dentistry 4 11%
Agricultural and Biological Sciences 3 9%
Nursing and Health Professions 1 3%
Other 6 17%
Unknown 11 31%