Title |
Genotype-driven recruitment: a strategy whose time has come?
|
---|---|
Published in |
BMC Medical Genomics, May 2013
|
DOI | 10.1186/1755-8794-6-19 |
Pubmed ID | |
Authors |
Isabelle Budin-Ljøsne, Kaitlin J Soye, Anne Marie Tassé, Bartha Maria Knoppers, Jennifer R Harris |
Abstract |
Genotype-Driven Recruitment (GDR) is a research design that recruits research participants based on genotype rather than based on the presence or absence of a particular condition or clinical outcome. Analyses of the ethical issues of GDR studies, and the recommendations derived from these analyses, are based on GDR research designs that make use of genetic information already collected in previous studies. However, as genotyping becomes more affordable, it is expected that genotypic information will become a common part of the information stored in biobanks and held in health care records. Furthermore, individuals will increasingly gain knowledge of their own genotypes through Direct-to-Consumer services. One can therefore foresee that individuals will be invited to participate not only in follow-up GDR studies but also in original GDR studies because genetic information about them is available. These individuals may or may have not participated in research before and may or may not be aware that their genetic information is available for research. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 4 | 40% |
Colombia | 1 | 10% |
United States | 1 | 10% |
Unknown | 4 | 40% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 70% |
Science communicators (journalists, bloggers, editors) | 1 | 10% |
Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Scientists | 1 | 10% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 3% |
Unknown | 32 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 10 | 30% |
Student > Ph. D. Student | 5 | 15% |
Student > Master | 4 | 12% |
Student > Bachelor | 3 | 9% |
Student > Doctoral Student | 2 | 6% |
Other | 7 | 21% |
Unknown | 2 | 6% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 9 | 27% |
Biochemistry, Genetics and Molecular Biology | 6 | 18% |
Social Sciences | 5 | 15% |
Agricultural and Biological Sciences | 3 | 9% |
Business, Management and Accounting | 1 | 3% |
Other | 5 | 15% |
Unknown | 4 | 12% |