Title |
Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays
|
---|---|
Published in |
BMC Infectious Diseases, May 2013
|
DOI | 10.1186/1471-2334-13-240 |
Pubmed ID | |
Authors |
Danila V Zimenkov, Olga V Antonova, Alexey V Kuz’min, Yulia D Isaeva, Ludmila Y Krylova, Sergey A Popov, Alexander S Zasedatelev, Vladimir M Mikhailovich, Dmitry A Gryadunov |
Abstract |
The steady rise in the spread of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) requires rapid and reliable methods to identify resistant strains. The current molecular methods to detect MTB resistance to second-line drugs either do not cover an extended spectrum of mutations to be identified or are not easily implemented in clinical laboratories. A rapid molecular technique for the detection of resistance to second-line drugs in M. tuberculosis has been developed using hybridisation analysis on microarrays. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 1% |
Germany | 1 | 1% |
Unknown | 71 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 19% |
Student > Ph. D. Student | 12 | 16% |
Student > Master | 9 | 12% |
Student > Postgraduate | 8 | 11% |
Other | 7 | 10% |
Other | 9 | 12% |
Unknown | 14 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 25% |
Medicine and Dentistry | 15 | 21% |
Biochemistry, Genetics and Molecular Biology | 9 | 12% |
Immunology and Microbiology | 5 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Other | 5 | 7% |
Unknown | 18 | 25% |