↓ Skip to main content

Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment

Overview of attention for article published in BMC Genomics, May 2013
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
108 Dimensions

Readers on

mendeley
182 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment
Published in
BMC Genomics, May 2013
DOI 10.1186/1471-2164-14-348
Pubmed ID
Authors

Ryan Y Wong, Sarah E Oxendine, John Godwin

Abstract

Stress and anxiety-related behaviors are seen in many organisms. Studies have shown that in humans and other animals, treatment with selective serotonin reuptake inhibitors (e.g. fluoxetine) can reduce anxiety and anxiety-related behaviors. The efficacies and side effects, however, can vary between individuals. Fluoxetine can modulate anxiety in a stereospecific manner or with equal efficacy regardless of stereoisomer depending on the mechanism of action (e.g. serotonergic or GABAergic effects). Zebrafish are an emerging and valuable translational model for understanding human health related issues such as anxiety. In this study we present data showing the behavioral and whole brain transcriptome changes with fluoxetine treatment in wild-derived zebrafish and suggest additional molecular mechanisms of this widely-prescribed drug.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 182 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 4 2%
United States 2 1%
United Kingdom 1 <1%
Japan 1 <1%
Unknown 174 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 20%
Student > Bachelor 33 18%
Student > Master 30 16%
Researcher 17 9%
Student > Postgraduate 6 3%
Other 22 12%
Unknown 38 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 53 29%
Biochemistry, Genetics and Molecular Biology 22 12%
Neuroscience 14 8%
Environmental Science 13 7%
Pharmacology, Toxicology and Pharmaceutical Science 12 7%
Other 20 11%
Unknown 48 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2013.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from BMC Genomics
#9,840
of 11,244 outputs
Outputs of similar age
#182,758
of 207,926 outputs
Outputs of similar age from BMC Genomics
#160
of 175 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,926 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 175 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.