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Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus

Overview of attention for article published in Arthritis Research & Therapy, April 2012
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1 Redditor

Citations

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40 Mendeley
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Title
Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus
Published in
Arthritis Research & Therapy, April 2012
DOI 10.1186/ar3803
Pubmed ID
Authors

Shui-Lian Yu, Paul KS Chan, Chun-Kwok Wong, Cheuk-Chun Szeto, Suzanne C Ho, Karine So, May MY Yu, So-Fan Yim, Tak-Hong Cheung, Martin CS Wong, Jo LK Cheung, Apple CM Yeung, Edmund K Li, Lai-Shan Tam

Abstract

Prevalence of an abnormal Papanicolaou smear was significantly increased in lupus patients in cross-sectional studies, associated with a higher prevalence of high-risk human papillomavirus (HPV) infection. The nucleic acid-specific Toll-like receptors (TLRs) locate at the endolysosomal compartments and trigger the induction of cytokines for the innate immune response. This study evaluated whether abnormal host innate immune response in lupus patients may enhance HPV persistence.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Switzerland 1 3%
Unknown 38 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 18%
Professor 6 15%
Student > Ph. D. Student 5 13%
Researcher 4 10%
Student > Doctoral Student 3 8%
Other 9 23%
Unknown 6 15%
Readers by discipline Count As %
Medicine and Dentistry 17 43%
Agricultural and Biological Sciences 10 25%
Immunology and Microbiology 2 5%
Psychology 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 0 0%
Unknown 9 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2013.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#3,132
of 3,381 outputs
Outputs of similar age
#158,420
of 174,273 outputs
Outputs of similar age from Arthritis Research & Therapy
#63
of 67 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,273 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.