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Functional divergence of the brain-size regulating gene MCPH1during primate evolution and the origin of humans

Overview of attention for article published in BMC Biology, May 2013
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Title
Functional divergence of the brain-size regulating gene MCPH1during primate evolution and the origin of humans
Published in
BMC Biology, May 2013
DOI 10.1186/1741-7007-11-62
Pubmed ID
Authors

Lei Shi, Ming Li, Qiang Lin, Xuebin Qi, Bing Su

Abstract

One of the key genes that regulate human brain size, MCPH1 has evolved under strong Darwinian positive selection during the evolution of primates. During this evolution, the divergence of MCPH1 protein sequences among primates may have caused functional changes that contribute to brain enlargement.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Germany 1 2%
Unknown 52 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 15%
Researcher 8 15%
Student > Ph. D. Student 8 15%
Student > Bachelor 6 11%
Other 5 9%
Other 8 15%
Unknown 11 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 30%
Biochemistry, Genetics and Molecular Biology 9 17%
Medicine and Dentistry 5 9%
Neuroscience 3 6%
Social Sciences 3 6%
Other 4 7%
Unknown 14 26%