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microRNA-mediated regulation of innate immune response in rheumatic diseases

Overview of attention for article published in Arthritis Research & Therapy, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
1 news outlet
twitter
1 tweeter

Citations

dimensions_citation
30 Dimensions

Readers on

mendeley
40 Mendeley
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Title
microRNA-mediated regulation of innate immune response in rheumatic diseases
Published in
Arthritis Research & Therapy, January 2013
DOI 10.1186/ar4194
Pubmed ID
Authors

Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen, Yihong Yao

Abstract

miRNAs have been shown to play essential regulatory roles in the innate immune system. They function at multiple levels to shape the innate immune response and maintain homeostasis by direct suppression of the expression of their target proteins, preferentially crucial signaling components and transcription factors. Studies in humans and in disease models have revealed that dysregulation of several miRNAs such as miR-146a and miR-155 in rheumatic diseases leads to aberrant production of and/or signaling by inflammatory cytokines and, thus, critically contributes to disease pathogenesis. In addition, the recent description of the role of certain extracellular miRNAs as innate immune agonist to induce inflammatory response would have direct relevance to rheumatic diseases.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 39 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 33%
Researcher 9 23%
Student > Master 5 13%
Student > Bachelor 4 10%
Other 2 5%
Other 5 13%
Unknown 2 5%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 28%
Agricultural and Biological Sciences 11 28%
Medicine and Dentistry 10 25%
Immunology and Microbiology 4 10%
Psychology 1 3%
Other 1 3%
Unknown 2 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2015.
All research outputs
#558,255
of 5,187,054 outputs
Outputs from Arthritis Research & Therapy
#174
of 1,243 outputs
Outputs of similar age
#12,402
of 95,400 outputs
Outputs of similar age from Arthritis Research & Therapy
#2
of 21 outputs
Altmetric has tracked 5,187,054 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,243 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,400 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.