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Comparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parameters

Overview of attention for article published in Reproductive Biology and Endocrinology, December 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

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Title
Comparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parameters
Published in
Reproductive Biology and Endocrinology, December 2016
DOI 10.1186/s12958-016-0219-0
Pubmed ID
Authors

Markus Lipovac, Florian Bodner, Martin Imhof, Peter Chedraui

Abstract

There are reports showing that l-carnitine alone or in combination with other micronutrients improve sperm parameters. However, comparative studies are still lacking. This study was carried out to compare the short term effects of a combination of eight micronutrients including l-carnitine vs. a mono-substance (l-carnitine alone) on sperm parameters. This was a prospective, open-labelled, nonrandomized study that included male subjects (20 to 60 years) with at least 1 year of subfertility and at least one pathological semen analysis who received 3 months treatment with a mono-substance (500 mg l-carnitine/twice a day, n = 156) or a combined compound (440 mg l-carnitine + 250 mg l-arginine + 40 mg zinc + 120 mg vitamin E + 80 mg glutathione + 60 μg selenium + 15 mg coenzyme Q10 + 800 μg folic acid/once a day, n = 143) for the same time period. Sperm parameters were analyzed before and after treatment and groups comparisons performed. Baseline characteristics were similar among studied groups (age and body mass indices). Semen parameters (volume, density, overall progressive motility [including slow and fast motility]) and percentage of sperm with normal morphology improved after 3 months in both groups as compared to baseline. However, relative change (expressed as % increase of absolute values) for sperm density and overall progressive motility (including fast motility) was found to be higher for the combined micronutrient treatment group as compared to the mono-treatment using l-carnitine alone. Both analyzed groups displayed a positive short term effect on all sperm parameters; however effect on density and motility was significantly better for the combined formulation. There is need for more research in this matter that includes long term outcome data. Retrospectively registered at ISRCTN (7th October 2016). Study ID: ISRCTN48594239.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 85 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 15%
Student > Master 13 15%
Other 11 13%
Student > Bachelor 9 11%
Student > Postgraduate 5 6%
Other 11 13%
Unknown 23 27%
Readers by discipline Count As %
Medicine and Dentistry 28 33%
Agricultural and Biological Sciences 5 6%
Nursing and Health Professions 5 6%
Biochemistry, Genetics and Molecular Biology 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 8 9%
Unknown 32 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2018.
All research outputs
#1,799,899
of 23,314,015 outputs
Outputs from Reproductive Biology and Endocrinology
#77
of 1,002 outputs
Outputs of similar age
#38,343
of 421,766 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#2
of 12 outputs
Altmetric has tracked 23,314,015 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,002 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,766 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.