You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG
|
|---|---|
| Published in |
Acta Neuropathologica Communications, May 2013
|
| DOI | 10.1186/2051-5960-1-18 |
| Pubmed ID | |
| Authors |
Anna C Navis, Simone P Niclou, Fred Fack, Daniel Stieber, Sanne van Lith, Kiek Verrijp, Alan Wright, Jonathan Stauber, Bastiaan Tops, Irene Otte-Holler, Ron A Wevers, Arno van Rooij, Stefan Pusch, Andreas von Deimling, Wikky Tigchelaar, Cornelis JF van Noorden, Pieter Wesseling, William PJ Leenders |
| Abstract |
Point mutations in genes encoding NADP+-dependent isocitrate dehydrogenases (especially IDH1) are common in lower grade diffuse gliomas and secondary glioblastomas and occur early during tumor development. The contribution of these mutations to gliomagenesis is not completely understood and research is hampered by the lack of relevant tumor models. We previously described the development of the patient-derived high-grade oligodendroglioma xenograft model E478 that carries the commonly occurring IDH1-R132H mutation. We here report on the analyses of E478 xenografts at the genetic, histologic and metabolic level. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| United Kingdom | 1 | 1% |
| Unknown | 73 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 22% |
| Student > Ph. D. Student | 16 | 21% |
| Student > Master | 12 | 16% |
| Other | 5 | 7% |
| Student > Doctoral Student | 5 | 7% |
| Other | 12 | 16% |
| Unknown | 9 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 25 | 33% |
| Medicine and Dentistry | 18 | 24% |
| Agricultural and Biological Sciences | 14 | 18% |
| Neuroscience | 3 | 4% |
| Chemistry | 3 | 4% |
| Other | 4 | 5% |
| Unknown | 9 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2018.
All research outputs
#6,392,410
of 22,711,242 outputs
Outputs from Acta Neuropathologica Communications
#910
of 1,366 outputs
Outputs of similar age
#54,271
of 195,178 outputs
Outputs of similar age from Acta Neuropathologica Communications
#8
of 33 outputs
Altmetric has tracked 22,711,242 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,366 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,178 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.