Title |
Mutations in many genes affect aggressive behavior in Drosophila melanogaster
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Published in |
BMC Biology, June 2009
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DOI | 10.1186/1741-7007-7-29 |
Pubmed ID | |
Authors |
Alexis C Edwards, Liesbeth Zwarts, Akihiko Yamamoto, Patrick Callaerts, Trudy FC Mackay |
Abstract |
Aggressive behavior in animals is important for survival and reproduction. Identifying the underlying genes and environmental contexts that affect aggressive behavior is important for understanding the evolutionary forces that maintain variation for aggressive behavior in natural populations, and to develop therapeutic interventions to modulate extreme levels of aggressive behavior in humans. While the role of neurotransmitters and a few other molecules in mediating and modulating levels of aggression is well established, it is likely that many additional genetic pathways remain undiscovered. Drosophila melanogaster has recently been established as an excellent model organism for studying the genetic basis of aggressive behavior. Here, we present the results of a screen of 170 Drosophila P-element insertional mutations for quantitative differences in aggressive behavior from their co-isogenic control line. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 4 | 3% |
Germany | 2 | 1% |
United States | 2 | 1% |
Canada | 2 | 1% |
Switzerland | 1 | <1% |
Spain | 1 | <1% |
China | 1 | <1% |
Unknown | 137 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 45 | 30% |
Researcher | 29 | 19% |
Student > Bachelor | 22 | 15% |
Student > Master | 16 | 11% |
Professor | 7 | 5% |
Other | 19 | 13% |
Unknown | 12 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 98 | 65% |
Biochemistry, Genetics and Molecular Biology | 14 | 9% |
Neuroscience | 6 | 4% |
Medicine and Dentistry | 4 | 3% |
Environmental Science | 2 | 1% |
Other | 8 | 5% |
Unknown | 18 | 12% |