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Mutations in many genes affect aggressive behavior in Drosophila melanogaster

Overview of attention for article published in BMC Biology, June 2009
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Title
Mutations in many genes affect aggressive behavior in Drosophila melanogaster
Published in
BMC Biology, June 2009
DOI 10.1186/1741-7007-7-29
Pubmed ID
Authors

Alexis C Edwards, Liesbeth Zwarts, Akihiko Yamamoto, Patrick Callaerts, Trudy FC Mackay

Abstract

Aggressive behavior in animals is important for survival and reproduction. Identifying the underlying genes and environmental contexts that affect aggressive behavior is important for understanding the evolutionary forces that maintain variation for aggressive behavior in natural populations, and to develop therapeutic interventions to modulate extreme levels of aggressive behavior in humans. While the role of neurotransmitters and a few other molecules in mediating and modulating levels of aggression is well established, it is likely that many additional genetic pathways remain undiscovered. Drosophila melanogaster has recently been established as an excellent model organism for studying the genetic basis of aggressive behavior. Here, we present the results of a screen of 170 Drosophila P-element insertional mutations for quantitative differences in aggressive behavior from their co-isogenic control line.

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The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 3%
Germany 2 1%
United States 2 1%
Canada 2 1%
Switzerland 1 <1%
Spain 1 <1%
China 1 <1%
Unknown 137 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 45 30%
Researcher 29 19%
Student > Bachelor 22 15%
Student > Master 16 11%
Professor 7 5%
Other 19 13%
Unknown 12 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 98 65%
Biochemistry, Genetics and Molecular Biology 14 9%
Neuroscience 6 4%
Medicine and Dentistry 4 3%
Environmental Science 2 1%
Other 8 5%
Unknown 18 12%