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Dysregulation of MicroRNAs in cancer

Overview of attention for article published in Journal of Biomedical Science, October 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

twitter
1 tweeter
patent
1 patent

Citations

dimensions_citation
105 Dimensions

Readers on

mendeley
113 Mendeley
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Title
Dysregulation of MicroRNAs in cancer
Published in
Journal of Biomedical Science, October 2012
DOI 10.1186/1423-0127-19-90
Pubmed ID
Authors

Pai-Sheng Chen, Jen-Liang Su, Mien-Chie Hung

Abstract

MicroRNAs (miRNAs) are involved in multiple biological activities as well as disease progression including cancer. Interestingly, miRNAs could act as either tumor suppressors or oncogenes depending on the functions of their targets. Using high-throughput profiling, dysregulation of miRNAs has been widely observed in different stages of cancer, and there is mounting evidence demonstrating several misguided mechanisms that cause miRNA dysregulation. In this review, we summarize the key functions of miRNAs in cancer, especially those affecting tumor metastasis and drug resistance. Moreover, the mechanisms leading to dysregulation of miRNAs, including genomic abnormalities, DNA/histone modifications, transcriptional regulation, abnormal biogenesis, and interaction between miRNAs, are also discussed.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 2%
India 1 <1%
Malaysia 1 <1%
Turkey 1 <1%
Russia 1 <1%
Hungary 1 <1%
Poland 1 <1%
Unknown 105 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 20%
Student > Ph. D. Student 22 19%
Student > Master 18 16%
Student > Doctoral Student 9 8%
Student > Bachelor 7 6%
Other 16 14%
Unknown 18 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 41 36%
Medicine and Dentistry 21 19%
Biochemistry, Genetics and Molecular Biology 21 19%
Chemical Engineering 2 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 <1%
Other 5 4%
Unknown 22 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2017.
All research outputs
#2,192,116
of 9,553,895 outputs
Outputs from Journal of Biomedical Science
#69
of 432 outputs
Outputs of similar age
#29,579
of 129,358 outputs
Outputs of similar age from Journal of Biomedical Science
#2
of 7 outputs
Altmetric has tracked 9,553,895 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 432 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 129,358 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.