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In silico engineering of aggregation-prone recombinant proteins for substrate recognition by the chaperonin GroEL

Overview of attention for article published in BMC Genomics, December 2012
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Title
In silico engineering of aggregation-prone recombinant proteins for substrate recognition by the chaperonin GroEL
Published in
BMC Genomics, December 2012
DOI 10.1186/1471-2164-13-s7-s22
Pubmed ID
Authors

Vipul Kumar, Ankita Punetha, Durai Sundar, Tapan K Chaudhuri

Abstract

Molecular chaperones appear to have been evolved to facilitate protein folding in the cell through entrapment of folding intermediates on the interior of a large cavity formed between GroEL and its co-chaperonin GroES. They bind newly synthesized or non-native polypeptides through hydrophobic interactions and prevent their aggregation. Some proteins do not interact with GroEL, hence even though they are aggregation prone, cannot be assisted by GroEL for their folding.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 26%
Student > Doctoral Student 3 16%
Researcher 2 11%
Professor > Associate Professor 2 11%
Student > Master 2 11%
Other 3 16%
Unknown 2 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 37%
Agricultural and Biological Sciences 5 26%
Nursing and Health Professions 1 5%
Physics and Astronomy 1 5%
Chemistry 1 5%
Other 0 0%
Unknown 4 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2013.
All research outputs
#20,194,368
of 22,711,645 outputs
Outputs from BMC Genomics
#9,250
of 10,626 outputs
Outputs of similar age
#247,367
of 278,911 outputs
Outputs of similar age from BMC Genomics
#344
of 381 outputs
Altmetric has tracked 22,711,645 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,626 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,911 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 381 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.