Title |
Tc-knirps plays different roles in the specification of antennal and mandibular parasegment boundaries and is regulated by a pair-rule gene in the beetle Tribolium castaneum
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Published in |
BMC Developmental Biology, June 2013
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DOI | 10.1186/1471-213x-13-25 |
Pubmed ID | |
Authors |
Andrew D Peel, Julia Schanda, Daniela Grossmann, Frank Ruge, Georg Oberhofer, Anna F Gilles, Johannes B Schinko, Martin Klingler, Gregor Bucher |
Abstract |
The Drosophila larval head is evolutionarily derived at the genetic and morphological level. In the beetle Tribolium castaneum, development of the larval head more closely resembles the ancestral arthropod condition. Unlike in Drosophila, a knirps homologue (Tc-kni) is required for development of the antennae and mandibles. However, published Tc-kni data are restricted to cuticle phenotypes and Tc-even-skipped and Tc-wingless stainings in knockdown embryos. Hence, it has remained unclear whether the entire antennal and mandibular segments depend on Tc-kni function, and whether the intervening intercalary segment is formed completely. We address these questions with a detailed examination of Tc-kni function. |
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Unknown | 22 | 81% |
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Student > Ph. D. Student | 7 | 26% |
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Student > Bachelor | 2 | 7% |
Other | 2 | 7% |
Unknown | 2 | 7% |
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Unknown | 4 | 15% |