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Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer’s disease

Overview of attention for article published in Lipids in Health and Disease, November 2012
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Title
Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer’s disease
Published in
Lipids in Health and Disease, November 2012
DOI 10.1186/1476-511x-11-163
Pubmed ID
Authors

Zhijie Xiao, Juan Wang, Weirong Chen, Peng Wang, Houlin Zeng, Weixi Chen

Abstract

Accumulating evidence suggested that dysregulation of cholesterol homeostasis might be a major etiologic factor in initiating and promoting neurodegeneration in Alzheimer's disease (AD). ATP-binding cassette transporter A1 (ABCA1), hepatic lipase (HL, coding genes named LIPC) and cholesteryl ester transfer protein (CETP) are important components of high-density lipoprotein (HDL) metabolism and reverse cholesterol transport (RCT) implicated in atherosclerosis and neurodegenerative diseases. In the present study, we will investigate the possible association of several common polymorphisms (ABCA1R219K, CETPTaqIB and LIPC-250 G/A) with susceptibility to AD and plasma lipid levels.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Czechia 1 2%
Italy 1 2%
Unknown 53 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 20%
Student > Ph. D. Student 10 18%
Student > Bachelor 9 16%
Student > Postgraduate 6 11%
Researcher 3 5%
Other 8 15%
Unknown 8 15%
Readers by discipline Count As %
Medicine and Dentistry 13 24%
Agricultural and Biological Sciences 11 20%
Biochemistry, Genetics and Molecular Biology 6 11%
Nursing and Health Professions 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 6 11%
Unknown 12 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2013.
All research outputs
#14,627,617
of 22,712,476 outputs
Outputs from Lipids in Health and Disease
#735
of 1,438 outputs
Outputs of similar age
#171,111
of 276,965 outputs
Outputs of similar age from Lipids in Health and Disease
#19
of 26 outputs
Altmetric has tracked 22,712,476 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,438 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,965 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.