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Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways

Overview of attention for article published in BMC Medical Genomics, June 2013
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Title
Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways
Published in
BMC Medical Genomics, June 2013
DOI 10.1186/1755-8794-6-22
Pubmed ID
Authors

Cecilia Mancini, Paola Roncaglia, Alessandro Brussino, Giovanni Stevanin, Nicola Lo Buono, Helena Krmac, Francesca Maltecca, Elena Gazzano, Anna Bartoletti Stella, Maria Antonietta Calvaruso, Luisa Iommarini, Claudia Cagnoli, Sylvie Forlani, Isabelle Le Ber, Alexandra Durr, Alexis Brice, Dario Ghigo, Giorgio Casari, Anna Maria Porcelli, Ada Funaro, Giuseppe Gasparre, Stefano Gustincich, Alfredo Brusco

Abstract

SCA28 is an autosomal dominant ataxia associated with AFG3L2 gene mutations. We performed a whole genome expression profiling using lymphoblastoid cell lines (LCLs) from four SCA28 patients and six unrelated healthy controls matched for sex and age.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 31%
Other 5 11%
Researcher 4 9%
Student > Postgraduate 4 9%
Student > Bachelor 3 7%
Other 7 16%
Unknown 8 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 24%
Agricultural and Biological Sciences 11 24%
Medicine and Dentistry 5 11%
Neuroscience 5 11%
Social Sciences 1 2%
Other 3 7%
Unknown 9 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 June 2013.
All research outputs
#20,195,024
of 22,712,476 outputs
Outputs from BMC Medical Genomics
#996
of 1,215 outputs
Outputs of similar age
#172,306
of 196,784 outputs
Outputs of similar age from BMC Medical Genomics
#12
of 15 outputs
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So far Altmetric has tracked 1,215 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.