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Ambushing the ambush hypothesis: predicting and evaluating off-frame codon frequencies in Prokaryotic Genomes

Overview of attention for article published in BMC Genomics, June 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

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3 X users
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4 Wikipedia pages

Citations

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9 Dimensions

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18 Mendeley
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Title
Ambushing the ambush hypothesis: predicting and evaluating off-frame codon frequencies in Prokaryotic Genomes
Published in
BMC Genomics, June 2013
DOI 10.1186/1471-2164-14-418
Pubmed ID
Authors

David W Morgens, Charlotte H Chang, Andre RO Cavalcanti

Abstract

In this paper, we address the evidence for the Ambush Hypothesis. Proposed by Seligmann and Pollock, this hypothesis posits that there exists a selection for off-frame stop codons (OSCs) to counteract the possible deleterious effects of translational frameshifts, including the waste of resources and potential cytotoxicity. Two main types of study have been used to support the hypothesis. Some studies analyzed codon usage and showed that codons with more potential to create OSCs seem to be favored over codons with lower potential; they used this finding to support the Ambush Hypothesis. Another study used 342 bacterial genomes to evaluate the hypothesis directly, finding significant excesses of OSCs in these genomes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 6%
Germany 1 6%
Unknown 16 89%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 22%
Student > Master 3 17%
Other 2 11%
Researcher 2 11%
Student > Ph. D. Student 2 11%
Other 3 17%
Unknown 2 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 39%
Biochemistry, Genetics and Molecular Biology 4 22%
Computer Science 2 11%
Immunology and Microbiology 1 6%
Medicine and Dentistry 1 6%
Other 0 0%
Unknown 3 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2022.
All research outputs
#6,782,242
of 23,881,329 outputs
Outputs from BMC Genomics
#2,966
of 10,793 outputs
Outputs of similar age
#55,829
of 199,266 outputs
Outputs of similar age from BMC Genomics
#31
of 117 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 10,793 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,266 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.