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The role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary disease

Overview of attention for article published in Respiratory Research, June 2013
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2 X users

Citations

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55 Mendeley
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Title
The role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary disease
Published in
Respiratory Research, June 2013
DOI 10.1186/1465-9921-14-67
Pubmed ID
Authors

Qin Wang, Yunshan Wang, Yi Zhang, Yuke Zhang, Wei Xiao

Abstract

Epithelial-mesenchymal transition (EMT) plays a crucial role in small airway fibrosis of patients with chronic obstructive pulmonary disease (COPD). Increasing evidence suggests that the urokinase plasminogen activator receptor (uPAR) is involved in the pathogenesis of COPD. Increased uPAR expression has been implicated in the promotion of EMT in numerous cancers; however the role of uPAR in EMT in small airway epithelial cells of patients with COPD remains unclear. In this study, we investigated the degree of EMT and uPAR expression in lung epithelium of COPD patients, and verified the effect of uPAR on cigarette smoke extract (CSE)-induced EMT in vitro.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
United States 1 2%
Russia 1 2%
Unknown 52 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 20%
Student > Bachelor 10 18%
Student > Ph. D. Student 8 15%
Student > Postgraduate 4 7%
Professor > Associate Professor 3 5%
Other 9 16%
Unknown 10 18%
Readers by discipline Count As %
Medicine and Dentistry 18 33%
Biochemistry, Genetics and Molecular Biology 10 18%
Agricultural and Biological Sciences 9 16%
Immunology and Microbiology 3 5%
Nursing and Health Professions 1 2%
Other 3 5%
Unknown 11 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2013.
All research outputs
#16,045,990
of 25,371,288 outputs
Outputs from Respiratory Research
#1,890
of 3,062 outputs
Outputs of similar age
#120,795
of 207,734 outputs
Outputs of similar age from Respiratory Research
#13
of 28 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,734 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.