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Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow-derived cells

Overview of attention for article published in BMC Musculoskeletal Disorders, July 2013
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2 X users

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Title
Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow-derived cells
Published in
BMC Musculoskeletal Disorders, July 2013
DOI 10.1186/1471-2474-14-197
Pubmed ID
Authors

Hiroki Yokota, Kazunori Hamamura, Andy Chen, Todd R Dodge, Nancy Tanjung, Aysan Abedinpoor, Ping Zhang

Abstract

Osteoporosis is a skeletal disease leading to an increased risk of bone fracture. Using a mouse osteoporosis model induced by administration of a receptor activator of nuclear factor kappa-B ligand (RANKL), salubrinal was recently reported as a potential therapeutic agent. To evaluate the role of salubrinal in cellular fates as well as migratory and adhesive functions of osteoclast/osteoblast precursors, we examined the development of primary bone marrow-derived cells in the presence and absence of salubrinal. We addressed a question: are salubrinal's actions more potent to the cells isolated from the osteoporotic mice than those isolated from the control mice?

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 27%
Student > Bachelor 2 13%
Student > Ph. D. Student 2 13%
Researcher 2 13%
Student > Master 2 13%
Other 2 13%
Unknown 1 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 33%
Biochemistry, Genetics and Molecular Biology 3 20%
Medicine and Dentistry 2 13%
Physics and Astronomy 1 7%
Engineering 1 7%
Other 0 0%
Unknown 3 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2013.
All research outputs
#14,628,184
of 22,713,403 outputs
Outputs from BMC Musculoskeletal Disorders
#2,258
of 4,030 outputs
Outputs of similar age
#114,393
of 194,634 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#48
of 75 outputs
Altmetric has tracked 22,713,403 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,030 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,634 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.