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Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade

Overview of attention for article published in BMC Cancer, July 2013
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  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

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3 X users
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1 Facebook page

Citations

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100 Dimensions

Readers on

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74 Mendeley
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Title
Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade
Published in
BMC Cancer, July 2013
DOI 10.1186/1471-2407-13-327
Pubmed ID
Authors

Mingo Ming Ho Yung, David Wai Chan, Vincent Wing Sun Liu, Kwok-Ming Yao, Hextan Yuen-Sheung Ngan

Abstract

Although advanced-stage cervical cancer can benefit from current treatments, approximately 30% patients may fail after definitive treatment eventually. Therefore, exploring alternative molecular therapeutic approaches is imperatively needed for this disease. We have recently shown that activation of AMP-activated protein kinase (AMPK), a metabolic sensor, hampers cervical cancer cell growth through blocking the Wnt/β-catenin signaling activity. Here, we report that activated AMPK (p-AMPK) also inhibits cervical cancer cell growth by counteracting FOXM1 function.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Italy 1 1%
Unknown 72 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 30%
Student > Bachelor 10 14%
Student > Doctoral Student 7 9%
Student > Master 7 9%
Researcher 6 8%
Other 7 9%
Unknown 15 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 21 28%
Agricultural and Biological Sciences 21 28%
Medicine and Dentistry 9 12%
Immunology and Microbiology 2 3%
Neuroscience 2 3%
Other 2 3%
Unknown 17 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2013.
All research outputs
#13,154,315
of 22,713,403 outputs
Outputs from BMC Cancer
#2,827
of 8,265 outputs
Outputs of similar age
#100,570
of 194,345 outputs
Outputs of similar age from BMC Cancer
#33
of 76 outputs
Altmetric has tracked 22,713,403 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,265 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,345 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.