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Intermediate-risk prostate cancer patients treated with androgen deprivation therapy and a hypofractionated radiation regimen with or without image guided radiotherapy

Overview of attention for article published in Radiation Oncology, June 2013
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1 tweeter
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1 Facebook page

Citations

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15 Dimensions

Readers on

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31 Mendeley
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Title
Intermediate-risk prostate cancer patients treated with androgen deprivation therapy and a hypofractionated radiation regimen with or without image guided radiotherapy
Published in
Radiation Oncology, June 2013
DOI 10.1186/1748-717x-8-137
Pubmed ID
Authors

Maurizio Valeriani, Stefano Bracci, Mattia Falchetto Osti, Teresa Falco, Linda Agolli, Vitaliana De Sanctis, Riccardo Maurizi Enrici

Abstract

BACKGROUND: To evaluate the efficacy of hypofractionated radiotherapy (HyRT) with or without image guided radiotherapy (IGRT) in intermediate risk prostate cancer. METHODS: 105 patients were treated with HyRT, 43,8 Gy and 54,75 Gy were delivered to the seminal vescicles and to the prostate, respectively; 3,65 Gy/fraction three times weekly. All patients underwent 9 months hormonal therapy. Patient position was verified with daily kV cone beam CT in 69 patients (IGRT group). Acute and late toxicities were evaluated according to RTOG scale. Biochemical relapse was defined using PSA nadir + 2 ng/mL. The data were prospectively collected and retrospectively analyzed to evaluate the efficacy of IGRT. RESULTS: After a median follow-up of 31 months the actuarial 3-year bNED was 93,7%. During RT, 10.5% and 7.6% of patients developed >=Grade 2 rectal and urinary toxicities, respectively. The cumulative incidence of >=Grade 2 late rectal and urinary toxicities at 3 years were 6,9%, and 10,8%, respectively. The incidence of >=Grade 2 late rectal toxicities was significant reduced in the IGRT group (1,6% vs. 14,5%, p=0,021). Two patients developed Grade 3 urethral obstruction and one patient developed grade 3 rectal bleeding. CONCLUSIONS: HyRT represents a well-tolerated treatment able to achieve a high bNED. The use of daily IGRT is beneficial for reducing the incidence of late toxicities.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 23%
Student > Bachelor 4 13%
Student > Doctoral Student 4 13%
Student > Ph. D. Student 3 10%
Librarian 2 6%
Other 4 13%
Unknown 7 23%
Readers by discipline Count As %
Medicine and Dentistry 14 45%
Nursing and Health Professions 3 10%
Economics, Econometrics and Finance 1 3%
Computer Science 1 3%
Sports and Recreations 1 3%
Other 3 10%
Unknown 8 26%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2013.
All research outputs
#2,921,586
of 4,507,280 outputs
Outputs from Radiation Oncology
#565
of 826 outputs
Outputs of similar age
#57,880
of 89,351 outputs
Outputs of similar age from Radiation Oncology
#25
of 35 outputs
Altmetric has tracked 4,507,280 research outputs across all sources so far. This one is in the 31st percentile – i.e., 31% of other outputs scored the same or lower than it.
So far Altmetric has tracked 826 research outputs from this source. They receive a mean Attention Score of 1.8. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 89,351 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.