Title |
Isolation and multilineage differentiation of bone marrow mesenchymal stem cells from abattoir-derived bovine fetuses
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Published in |
BMC Veterinary Research, July 2013
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DOI | 10.1186/1746-6148-9-133 |
Pubmed ID | |
Authors |
Yennifer Cortes, Margarita Ojeda, Diego Araya, Fernando Dueñas, María S Fernández, Oscar A Peralta |
Abstract |
Mesenchymal stem cells (MSC) are multipotent progenitor cells localized in the stromal compartment of the bone marrow (BM). The potential of MSC for mesenchymal differentiation has been well documented in different animal models predominantly on rodents. However, information regarding bovine MSC (bMSC) is limited, and the differentiation potential of bMSC derived from fetal BM remains unknown. In the present study we sought to isolate bMSC from abattoir-derived fetal BM and to characterize the multipotent and differentiation potential under osteogenic, chondrogenic and adipogenic conditions by quantitative and qualitative analyses. |
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Scientists | 1 | 50% |
Mendeley readers
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Professor | 3 | 5% |
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Other | 4 | 7% |
Unknown | 13 | 23% |