Title |
PKCγ Receptor Mediates Visceral Nociception and Hyperalgesia following Exposure to PTSD-Like Stress in the Spinal Cord of Rats
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Published in |
Molecular Pain, January 2013
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DOI | 10.1186/1744-8069-9-35 |
Pubmed ID | |
Authors |
Yu-Qin He, Qiang Chen, Lei Ji, Zheng-Guo Wang, Zhi-Hong Bai, Robert L Stephens, Min Yang |
Abstract |
Clinical studies indicate that patients with post-traumatic stress disorder (PTSD) frequently share comorbidity with numerous chronic pain conditions. However, the sustained effects of PTSD-like stress over time on visceral nociception and hyperalgesia have been rarely studied, and the underlying mechanisms of stress-induced modulation of visceral hyperalgesia remain elusive. The purpose of this study was to investigate the characterization of visceral nociception and hyperalgesia over time in rats exposed to PTSD-like stress, and to explore the potential role of protein kinase C gamma (PKCgamma) in mediating visceral hyperalgesia following exposure to PTSD-like stress. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Australia | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 36 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 9 | 25% |
Student > Bachelor | 6 | 17% |
Professor > Associate Professor | 3 | 8% |
Student > Master | 3 | 8% |
Professor | 2 | 6% |
Other | 4 | 11% |
Unknown | 9 | 25% |
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Psychology | 5 | 14% |
Neuroscience | 5 | 14% |
Medicine and Dentistry | 5 | 14% |
Agricultural and Biological Sciences | 4 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 8% |
Other | 4 | 11% |
Unknown | 10 | 28% |