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D-isoascorbyl palmitate: lipase-catalyzed synthesis, structural characterization and process optimization using response surface methodology

Overview of attention for article published in BMC Chemistry, July 2013
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Title
D-isoascorbyl palmitate: lipase-catalyzed synthesis, structural characterization and process optimization using response surface methodology
Published in
BMC Chemistry, July 2013
DOI 10.1186/1752-153x-7-114
Pubmed ID
Authors

Wen-Jing Sun, Hong-Xia Zhao, Feng-Jie Cui, Yun-Hong Li, Si-Lian Yu, Qiang Zhou, Jing-Ya Qian, Ying Dong

Abstract

Isoascorbic acid is a stereoisomer of L-ascorbic acid, and widely used as a food antioxidant. However, its highly hydrophilic behavior prevents its application in cosmetics or fats and oils-based foods. To overcome this problem, D-isoascorbyl palmitate was synthesized in the present study for improving the isoascorbic acid's oil solubility with an immobilized lipase in organic media. The structural information of synthesized product was clarified using LC-ESI-MS, FT-IR, 1H and 13C NMR analysis, and process parameters for high yield of D-isoascorbyl palmitate were optimized by using One-factor-at-a-time experiments and response surface methodology (RSM).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 33%
Researcher 7 23%
Student > Master 3 10%
Professor 2 7%
Other 2 7%
Other 3 10%
Unknown 3 10%
Readers by discipline Count As %
Chemistry 8 27%
Agricultural and Biological Sciences 7 23%
Biochemistry, Genetics and Molecular Biology 1 3%
Nursing and Health Professions 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 4 13%
Unknown 8 27%