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Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy

Overview of attention for article published in Epigenetics & Chromatin, July 2013
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Title
Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy
Published in
Epigenetics & Chromatin, July 2013
DOI 10.1186/1756-8935-6-18
Pubmed ID
Authors

Josef Davidsson, Srinivas Veerla, Bertil Johansson

Abstract

To investigate epigenetic patterns associated with aneuploidy we used constitutional trisomy 8 mosaicism (CT8M) as a model, enabling analyses of single cell clones, harboring either trisomy or disomy 8, from the same patient; this circumvents any bias introduced by using cells from unrelated, healthy individuals as controls. We profiled gene and miRNA expression as well as genome-wide and promoter specific DNA methylation and hydroxymethylation patterns in trisomic and disomic fibroblasts, using microarrays and methylated DNA immunoprecipitation.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
France 1 3%
Canada 1 3%
Unknown 27 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 27%
Student > Bachelor 6 20%
Student > Ph. D. Student 5 17%
Student > Doctoral Student 3 10%
Student > Postgraduate 3 10%
Other 4 13%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 43%
Biochemistry, Genetics and Molecular Biology 7 23%
Medicine and Dentistry 7 23%
Psychology 1 3%
Economics, Econometrics and Finance 1 3%
Other 0 0%
Unknown 1 3%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2013.
All research outputs
#13,891,799
of 22,714,025 outputs
Outputs from Epigenetics & Chromatin
#390
of 563 outputs
Outputs of similar age
#107,160
of 194,642 outputs
Outputs of similar age from Epigenetics & Chromatin
#10
of 13 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 563 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,642 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.