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Cardiac regeneration and diabetes

Overview of attention for article published in Regenerative Medicine Research, January 2014
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Mentioned by

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2 tweeters
facebook
1 Facebook page

Citations

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5 Dimensions

Readers on

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31 Mendeley
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Title
Cardiac regeneration and diabetes
Published in
Regenerative Medicine Research, January 2014
DOI 10.1186/2050-490x-2-1
Pubmed ID
Authors

Lu Cai, Bradley B Keller

Abstract

The prevalence of diabetes continues to increase world-wide and is a leading cause of morbidity, mortality, and rapidly rising health care costs. Although strict glucose control combined with good pharmacological and non-pharmacologic interventions can increase diabetic patient life span, the frequency and mortality of myocardial ischemia and infarction remain drastically increased in diabetic patients. Therefore, more effective therapeutic approaches are urgently needed. Over the past 15 years, cellular repair of the injured adult heart has become the focus of a rapidly expanding broad spectrum of pre-clinical and clinical research. Recent clinical trials have achieved favorable initial endpoints with improvements in cardiac function and clinical symptoms following cellular therapy. Due to the increased risk of cardiac disease, cardiac regeneration may be one strategy to treat patients with diabetic cardiomyopathy and/or myocardial infarction. However, pre-clinical studies suggest that the diabetic myocardium may not be a favorable environment for the transplantation and survival of stem cells due to altered kinetics in cellular homing, survival, and in situ remodeling. Therefore, unique conditions in the diabetic myocardium will require novel solutions in order to increase the efficiency of cellular repair following ischemia and/or infarction. This review briefly summarizes some of the recent advances in cardiac regeneration in non-diabetic conditions and then provides an overview of some of the issues related to diabetes that must be addressed in the coming years.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 26%
Researcher 7 23%
Student > Bachelor 3 10%
Student > Ph. D. Student 3 10%
Professor > Associate Professor 2 6%
Other 7 23%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 29%
Medicine and Dentistry 7 23%
Biochemistry, Genetics and Molecular Biology 6 19%
Economics, Econometrics and Finance 2 6%
Sports and Recreations 2 6%
Other 2 6%
Unknown 3 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2017.
All research outputs
#4,916,706
of 9,053,319 outputs
Outputs from Regenerative Medicine Research
#17
of 19 outputs
Outputs of similar age
#175,149
of 309,744 outputs
Outputs of similar age from Regenerative Medicine Research
#1
of 1 outputs
Altmetric has tracked 9,053,319 research outputs across all sources so far. This one is in the 27th percentile – i.e., 27% of other outputs scored the same or lower than it.
So far Altmetric has tracked 19 research outputs from this source. They receive a mean Attention Score of 2.0. This one scored the same or higher as 2 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,744 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them