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ACE-inhibition, but not weight reduction restores cardiomyocyte response to β-adrenergic stimulation in the metabolic syndrome

Overview of attention for article published in BMC Cardiovascular Disorders, July 2013
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Title
ACE-inhibition, but not weight reduction restores cardiomyocyte response to β-adrenergic stimulation in the metabolic syndrome
Published in
BMC Cardiovascular Disorders, July 2013
DOI 10.1186/1471-2261-13-51
Pubmed ID
Authors

Ines Nevelsteen, Virginie Bito, Gerry Van der Mieren, Annelies Vanderper, An Van den Bergh, Karin R Sipido, Kanigula Mubagwa, Paul Herijgers

Abstract

Diabetic cardiomyopathy is characterized by systolic and early diastolic ventricular dysfunction. In the metabolic syndrome (MS), ventricular stiffness is additionally increased in a later stage. It is unknown whether this is related to intrinsic cardiomyocyte dysfunction, extrinsic factors influencing cardiomyocyte contractility and/or cardiac function, or a combination of both. A first aim was to study cardiomyocyte contractility and Ca2+ handling in vitro in a mouse model of MS. A second aim was to investigate whether in vivo hypocaloric diet or ACE-inhibition (ACE-I) improved cardiomyocyte contractility in vitro, contractile reserve and Ca2+ handling.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Colombia 1 3%
Unknown 35 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 11%
Professor > Associate Professor 4 11%
Student > Master 4 11%
Professor 3 8%
Student > Ph. D. Student 3 8%
Other 9 24%
Unknown 10 27%
Readers by discipline Count As %
Medicine and Dentistry 11 30%
Agricultural and Biological Sciences 7 19%
Nursing and Health Professions 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Social Sciences 1 3%
Other 3 8%
Unknown 12 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2013.
All research outputs
#15,274,524
of 22,714,025 outputs
Outputs from BMC Cardiovascular Disorders
#823
of 1,595 outputs
Outputs of similar age
#120,300
of 194,569 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#9
of 18 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,595 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,569 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.