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Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators

Overview of attention for article published in Journal of Neuroinflammation, July 2013
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1 tweeter

Citations

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22 Dimensions

Readers on

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45 Mendeley

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Title
Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators
Published in
Journal of Neuroinflammation, July 2013
DOI 10.1186/1742-2094-10-81
Pubmed ID
23837880
Authors

Ara E Hinojosa, Javier R Caso, Borja García-Bueno, Juan C Leza, José LM Madrigal

Abstract

Noradrenaline (NA) is known to limit neuroinflammation. However, the previously described induction by NA of a chemokine involved in the progression of immune/inflammatory processes, such as chemokine (C-C motif) ligand 2 (CCL2)/monocyte chemotactic protein-1 (MCP-1), apparently contradicts NA anti-inflammatory actions. In the current study we analyzed NA regulation of astroglial chemokine (C-X3-C motif) ligand 1 (CX3CL1), also known as fractalkine, another chemokine to which both neuroprotective and neurodegenerative actions have been attributed. In addition, NA effects on other chemokines and pro-inflammatory mediators were also analyzed.

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Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 20%
Student > Bachelor 7 16%
Student > Ph. D. Student 6 13%
Other 4 9%
Researcher 4 9%
Other 12 27%
Unknown 3 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 33%
Neuroscience 10 22%
Medicine and Dentistry 6 13%
Biochemistry, Genetics and Molecular Biology 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 2 4%
Unknown 6 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2013.
All research outputs
#4,606,450
of 6,228,993 outputs
Outputs from Journal of Neuroinflammation
#642
of 897 outputs
Outputs of similar age
#61,586
of 90,292 outputs
Outputs of similar age from Journal of Neuroinflammation
#20
of 30 outputs
Altmetric has tracked 6,228,993 research outputs across all sources so far. This one is in the 15th percentile – i.e., 15% of other outputs scored the same or lower than it.
So far Altmetric has tracked 897 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,292 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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