Title |
Effects of probiotics in patients with diabetes mellitus type 2: study protocol for a randomized, double-blind, placebo-controlled trial
|
---|---|
Published in |
Trials, July 2013
|
DOI | 10.1186/1745-6215-14-195 |
Pubmed ID | |
Authors |
Majed S Alokail, Shaun Sabico, Yousef Al-Saleh, Nasser M Al-Daghri, Khalid M Alkharfy, Paul M Vanhoutte, Philip G McTernan |
Abstract |
Low grade chronic inflammation is observed in patients with type 2 diabetes mellitus (T2DM). Endotoxin derived from gut bacteria may act as a potent inflammatory stimulant. Probiotics, which are believed to contain health promoting live microorganisms, may influence circulating endotoxin levels. Ingestion of live probiotic cultures may alter gut microbiota in a beneficial manner to reduce inflammation; no information is available whether or not they do so in patients with T2DM. Therefore, the aim of this study is to characterize the beneficial effects of probiotics on circulating endotoxin levels and other biomarkers related to systemic low-grade inflammation in patients with T2DM. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Denmark | 1 | <1% |
Unknown | 210 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 38 | 18% |
Student > Bachelor | 37 | 18% |
Researcher | 23 | 11% |
Student > Ph. D. Student | 20 | 9% |
Other | 14 | 7% |
Other | 25 | 12% |
Unknown | 54 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 44 | 21% |
Agricultural and Biological Sciences | 37 | 18% |
Biochemistry, Genetics and Molecular Biology | 16 | 8% |
Nursing and Health Professions | 14 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 13 | 6% |
Other | 27 | 13% |
Unknown | 60 | 28% |