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Effects of probiotics in patients with diabetes mellitus type 2: study protocol for a randomized, double-blind, placebo-controlled trial

Overview of attention for article published in Trials, July 2013
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Title
Effects of probiotics in patients with diabetes mellitus type 2: study protocol for a randomized, double-blind, placebo-controlled trial
Published in
Trials, July 2013
DOI 10.1186/1745-6215-14-195
Pubmed ID
Authors

Majed S Alokail, Shaun Sabico, Yousef Al-Saleh, Nasser M Al-Daghri, Khalid M Alkharfy, Paul M Vanhoutte, Philip G McTernan

Abstract

Low grade chronic inflammation is observed in patients with type 2 diabetes mellitus (T2DM). Endotoxin derived from gut bacteria may act as a potent inflammatory stimulant. Probiotics, which are believed to contain health promoting live microorganisms, may influence circulating endotoxin levels. Ingestion of live probiotic cultures may alter gut microbiota in a beneficial manner to reduce inflammation; no information is available whether or not they do so in patients with T2DM. Therefore, the aim of this study is to characterize the beneficial effects of probiotics on circulating endotoxin levels and other biomarkers related to systemic low-grade inflammation in patients with T2DM.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 211 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 <1%
Unknown 210 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 38 18%
Student > Bachelor 37 18%
Researcher 23 11%
Student > Ph. D. Student 20 9%
Other 14 7%
Other 25 12%
Unknown 54 26%
Readers by discipline Count As %
Medicine and Dentistry 44 21%
Agricultural and Biological Sciences 37 18%
Biochemistry, Genetics and Molecular Biology 16 8%
Nursing and Health Professions 14 7%
Pharmacology, Toxicology and Pharmaceutical Science 13 6%
Other 27 13%
Unknown 60 28%