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Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors

Overview of attention for article published in Journal of Neuroinflammation, July 2013
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  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Mentioned by

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4 X users
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1 Facebook page

Citations

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117 Dimensions

Readers on

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110 Mendeley
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Title
Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors
Published in
Journal of Neuroinflammation, July 2013
DOI 10.1186/1742-2094-10-87
Pubmed ID
Authors

Marcus A Lawson, Jennifer M Parrott, Robert H McCusker, Robert Dantzer, Keith W Kelley, Jason C O’Connor

Abstract

Activation of the tryptophan degrading enzyme indoleamine-2,3-dioxygenase 1 (IDO1) is associated with the development of behavioral signs of depression. Systemic immune challenge induces IDO1 in both the periphery and the brain, leading to increased circulating and brain concentrations of kynurenines. However, whether IDO1 activity within the brain is necessary for the manifestation of depression-like behavior of mice following a central immune challenge remains to be elucidated.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
France 1 <1%
Unknown 107 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 18%
Researcher 19 17%
Student > Bachelor 13 12%
Student > Master 9 8%
Professor > Associate Professor 8 7%
Other 16 15%
Unknown 25 23%
Readers by discipline Count As %
Neuroscience 24 22%
Agricultural and Biological Sciences 17 15%
Medicine and Dentistry 13 12%
Biochemistry, Genetics and Molecular Biology 7 6%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 13 12%
Unknown 31 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2020.
All research outputs
#12,878,673
of 22,714,025 outputs
Outputs from Journal of Neuroinflammation
#1,356
of 2,612 outputs
Outputs of similar age
#98,757
of 196,607 outputs
Outputs of similar age from Journal of Neuroinflammation
#10
of 33 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,612 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,607 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.