Title |
Influence of Vitamin C and Vitamin E on testicular zinc content and testicular toxicity in lead exposed albino rats
|
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Published in |
BMC Pharmacology and Toxicology, December 2012
|
DOI | 10.1186/2050-6511-13-17 |
Pubmed ID | |
Authors |
Oluseyi C Ayinde, Sunday Ogunnowo, Rita A Ogedegbe |
Abstract |
Occupational and environmental exposures to lead remain a public health problem as lead alters physiological processes by inducing oxidative stress and mimicking divalent cations. This study was designed to investigate the effects of Vitamin C (VC) and Vitamin E (VE) on the reproductive function of lead exposed male rats. Experimental animals were exposed to oral doses of lead, VC and VE at 60 mg/kg body weight, 40 mg/kg body weight, and 150 mg/kg body weight respectively, while control animals received 0.9% saline solution. Oral administration spanned for six weeks after which changes in testicular redox status, lead deposition, testicular zinc content, serum androgen content, semen quality and testis histology were examined. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Germany | 1 | 1% |
Unknown | 70 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 10 | 14% |
Student > Master | 8 | 11% |
Researcher | 6 | 8% |
Student > Postgraduate | 5 | 7% |
Lecturer | 5 | 7% |
Other | 11 | 15% |
Unknown | 26 | 37% |
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Agricultural and Biological Sciences | 9 | 13% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
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Environmental Science | 3 | 4% |
Other | 10 | 14% |
Unknown | 30 | 42% |