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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Distribution and fate of HIV-1 unintegrated DNA species: a comprehensive update
|
|---|---|
| Published in |
AIDS Research and Therapy, February 2017
|
| DOI | 10.1186/s12981-016-0127-6 |
| Pubmed ID | |
| Authors |
Faysal Bin Hamid, Jinsun Kim, Cha-Gyun Shin |
| Abstract |
Reverse transcription of viral RNA and the subsequent integration of reverse transcripts are the classical early events of the HIV-1 life-cycle. Simultaneously, abundant unintegrated DNAs (uDNAs), are formed in cells ubiquitously. The uDNAs either undergo recombination or degradation or persist inactively for long periods in the nucleus as future resources. Among them, 2-LTR circles are considered a dead-end for viral spread. Their contribution to the HIV-1 infection is still poorly understood. Nevertheless, the preintegration transcription of the aberrant DNAs and the consequent alterations of cellular factors have already been reported. Since the major fate of the viral genome is to persist as episomal DNA, precise characterization is required for studying the biology of HIV-1. This review compiles the biochemical and genetic updates on uDNA in the HIV-1 life cycle and could provide direction to further study of their roles in HIV-1 replication and application in HIV-1 pathogenesis. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 68 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 25% |
| Student > Bachelor | 10 | 15% |
| Researcher | 8 | 12% |
| Student > Master | 7 | 10% |
| Other | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 16 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 24 | 35% |
| Agricultural and Biological Sciences | 11 | 16% |
| Immunology and Microbiology | 8 | 12% |
| Medicine and Dentistry | 4 | 6% |
| Computer Science | 1 | 1% |
| Other | 3 | 4% |
| Unknown | 17 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2017.
All research outputs
#14,331,382
of 22,953,506 outputs
Outputs from AIDS Research and Therapy
#303
of 554 outputs
Outputs of similar age
#174,847
of 307,002 outputs
Outputs of similar age from AIDS Research and Therapy
#11
of 17 outputs
Altmetric has tracked 22,953,506 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 554 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,002 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.