Title |
Fibril-mediated oligomerization of pilin-derived protein nanotubes
|
---|---|
Published in |
Journal of Nanobiotechnology, July 2013
|
DOI | 10.1186/1477-3155-11-24 |
Pubmed ID | |
Authors |
Anna Petrov, Stephanie Lombardo, Gerald F Audette |
Abstract |
Self-assembling protein nanotubes (PNTs) are an intriguing alternative to carbon nanotubes for applications in bionanotechnology, in part due to greater inherent biocompatibility. The type IV pilus of the gram negative bacteria Pseudomonas aeruginosa is a protein-based fibre composed of a single subunit, the type IV pilin. Engineered pilin monomers from P. aeruginosa strain K122-4 (ΔK122) have been shown to oligomerize into PNTs both in solution and at surfaces. In order to fully exploit PNTs in bionanotechonological settings, an in-depth understanding of their assembly, physical characteristics and robustness, both in solution and when constrained to surfaces, is required. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 3% |
Unknown | 30 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 26% |
Researcher | 5 | 16% |
Student > Master | 4 | 13% |
Student > Bachelor | 3 | 10% |
Other | 3 | 10% |
Other | 2 | 6% |
Unknown | 6 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 12 | 39% |
Biochemistry, Genetics and Molecular Biology | 5 | 16% |
Chemistry | 5 | 16% |
Medicine and Dentistry | 1 | 3% |
Immunology and Microbiology | 1 | 3% |
Other | 0 | 0% |
Unknown | 7 | 23% |