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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth
|
|---|---|
| Published in |
Nutrition Journal, July 2013
|
| DOI | 10.1186/1475-2891-12-103 |
| Pubmed ID | |
| Authors |
Bodo C Melnik, Swen Malte John, Gerd Schmitz |
| Abstract |
Milk has been recognized to represent a functionally active nutrient system promoting neonatal growth of mammals. Cell growth is regulated by the nutrient-sensitive kinase mechanistic target of rapamycin complex 1 (mTORC1). There is still a lack of information on the mechanisms of mTORC1 up-regulation by milk consumption. This review presents milk as a materno-neonatal relay system functioning by transfer of preferential amino acids, which increase plasma levels of glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), insulin, growth hormone (GH) and insulin-like growth factor-1 (IGF-1) for mTORC1 activation. Importantly, milk exosomes, which regularly contain microRNA-21, most likely represent a genetic transfection system enhancing mTORC1-driven metabolic processes. Whereas human breast milk is the ideal food for infants allowing appropriate postnatal growth and species-specific metabolic programming, persistent high milk signaling during adolescence and adulthood by continued cow´s milk consumption may promote mTORC1-driven diseases of civilization. |
X Demographics
The data shown below were collected from the profiles of 44 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | 11% |
| Spain | 4 | 9% |
| United States | 4 | 9% |
| Italy | 2 | 5% |
| Portugal | 1 | 2% |
| Brazil | 1 | 2% |
| France | 1 | 2% |
| Germany | 1 | 2% |
| Finland | 1 | 2% |
| Other | 7 | 16% |
| Unknown | 17 | 39% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 29 | 66% |
| Practitioners (doctors, other healthcare professionals) | 9 | 20% |
| Scientists | 6 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 274 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 268 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 52 | 19% |
| Student > Bachelor | 44 | 16% |
| Student > Master | 39 | 14% |
| Student > Ph. D. Student | 33 | 12% |
| Other | 16 | 6% |
| Other | 44 | 16% |
| Unknown | 46 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 74 | 27% |
| Medicine and Dentistry | 54 | 20% |
| Biochemistry, Genetics and Molecular Biology | 37 | 14% |
| Nursing and Health Professions | 30 | 11% |
| Veterinary Science and Veterinary Medicine | 4 | 1% |
| Other | 25 | 9% |
| Unknown | 50 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 71. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2024.
All research outputs
#592,290
of 25,138,857 outputs
Outputs from Nutrition Journal
#183
of 1,503 outputs
Outputs of similar age
#4,431
of 204,545 outputs
Outputs of similar age from Nutrition Journal
#6
of 38 outputs
Altmetric has tracked 25,138,857 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,503 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.5. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 204,545 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.