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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Myeloid derived suppressor cells – a new therapeutic target in the treatment of cancer
|
|---|---|
| Published in |
Journal for Immunotherapy of Cancer, July 2013
|
| DOI | 10.1186/2051-1426-1-10 |
| Pubmed ID | |
| Authors |
Robert Wesolowski, Joseph Markowitz, William E Carson |
| Abstract |
Myeloid Derived Suppressor Cells (MDSC) are a heterogeneous population of immature myeloid cells that are increased in states of cancer, inflammation and infection. In malignant states, MDSC are induced by tumor secreted growth factors. MDSC play an important part in suppression of host immune responses through several mechanisms such as production of arginase 1, release of reactive oxygen species and nitric oxide and secretion of immune-suppressive cytokines. This leads to a permissive immune environment necessary for the growth of malignant cells. MDSC may also contribute to angiogenesis and tumor invasion. This review focuses on currently available strategies to inhibit MDSC in the treatment of cancer. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 43% |
| France | 1 | 14% |
| Unknown | 3 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Scientists | 2 | 29% |
| Science communicators (journalists, bloggers, editors) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 344 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 1% |
| Netherlands | 2 | <1% |
| Chile | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 336 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 74 | 22% |
| Researcher | 70 | 20% |
| Student > Master | 36 | 10% |
| Student > Bachelor | 26 | 8% |
| Student > Doctoral Student | 25 | 7% |
| Other | 63 | 18% |
| Unknown | 50 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 83 | 24% |
| Medicine and Dentistry | 75 | 22% |
| Immunology and Microbiology | 45 | 13% |
| Biochemistry, Genetics and Molecular Biology | 39 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 4% |
| Other | 30 | 9% |
| Unknown | 57 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2020.
All research outputs
#2,267,362
of 25,373,627 outputs
Outputs from Journal for Immunotherapy of Cancer
#608
of 3,421 outputs
Outputs of similar age
#18,828
of 206,789 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#2
of 7 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,421 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,789 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.