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A randomized controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme (The seAFOod Polyp…

Overview of attention for article published in Trials, July 2013
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Title
A randomized controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme (The seAFOod Polyp Prevention Trial): study protocol for a randomized controlled trial
Published in
Trials, July 2013
DOI 10.1186/1745-6215-14-237
Pubmed ID
Authors

Mark A Hull, Anna C Sandell, Alan A Montgomery, Richard FA Logan, Gayle M Clifford, Colin J Rees, Paul M Loadman, Diane Whitham

Abstract

The naturally-occurring omega (omega)-3 polyunsaturated fatty acid (PUFA) eicosapentaenoic acid (EPA) reduces colorectal adenoma (polyp) number and size in patients with familial adenomatous polyposis. The safety profile and potential cardiovascular benefits associated with omega-3 PUFAs make EPA a strong candidate for colorectal cancer (CRC) chemoprevention, alone or in combination with aspirin, which itself has recognized anti-CRC activity. Colorectal adenoma number and size are recognized as biomarkers of future CRC risk and are established as surrogate end-points in CRC chemoprevention trials.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 112 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 16%
Student > Master 15 13%
Student > Ph. D. Student 14 13%
Student > Bachelor 11 10%
Student > Doctoral Student 7 6%
Other 22 20%
Unknown 25 22%
Readers by discipline Count As %
Medicine and Dentistry 42 38%
Nursing and Health Professions 10 9%
Agricultural and Biological Sciences 9 8%
Biochemistry, Genetics and Molecular Biology 8 7%
Neuroscience 2 2%
Other 12 11%
Unknown 29 26%