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The effects of probiotics on depressive symptoms in humans: a systematic review

Overview of attention for article published in Annals of General Psychiatry, February 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 470)
  • High Attention Score compared to outputs of the same age (99th percentile)

Mentioned by

news
52 news outlets
blogs
7 blogs
twitter
119 tweeters
patent
1 patent
facebook
13 Facebook pages
wikipedia
2 Wikipedia pages
googleplus
3 Google+ users
video
4 video uploaders

Citations

dimensions_citation
201 Dimensions

Readers on

mendeley
697 Mendeley
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Title
The effects of probiotics on depressive symptoms in humans: a systematic review
Published in
Annals of General Psychiatry, February 2017
DOI 10.1186/s12991-017-0138-2
Pubmed ID
Authors

Caroline J. K. Wallace, Roumen Milev

Abstract

Patients suffering from depression experience significant mood, anxiety, and cognitive symptoms. Currently, most antidepressants work by altering neurotransmitter activity in the brain to improve these symptoms. However, in the last decade, research has revealed an extensive bidirectional communication network between the gastrointestinal tract and the central nervous system, referred to as the "gut-brain axis." Advances in this field have linked psychiatric disorders to changes in the microbiome, making it a potential target for novel antidepressant treatments. The aim of this review is to analyze the current body of research assessing the effects of probiotics, on symptoms of depression in humans. A systematic search of five databases was performed and study selection was completed using the preferred reporting items for systematic reviews and meta-analyses process. Ten studies met criteria and were analyzed for effects on mood, anxiety, and cognition. Five studies assessed mood symptoms, seven studies assessed anxiety symptoms, and three studies assessed cognition. The majority of the studies found positive results on all measures of depressive symptoms; however, the strain of probiotic, the dosing, and duration of treatment varied widely and no studies assessed sleep. The evidence for probiotics alleviating depressive symptoms is compelling but additional double-blind randomized control trials in clinical populations are warranted to further assess efficacy.

Twitter Demographics

The data shown below were collected from the profiles of 119 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 697 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 <1%
Spain 1 <1%
Unknown 695 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 172 25%
Student > Master 112 16%
Student > Ph. D. Student 59 8%
Researcher 53 8%
Student > Postgraduate 45 6%
Other 109 16%
Unknown 147 21%
Readers by discipline Count As %
Medicine and Dentistry 121 17%
Nursing and Health Professions 87 12%
Agricultural and Biological Sciences 75 11%
Biochemistry, Genetics and Molecular Biology 69 10%
Neuroscience 48 7%
Other 124 18%
Unknown 173 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 520. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2022.
All research outputs
#31,028
of 20,023,934 outputs
Outputs from Annals of General Psychiatry
#1
of 470 outputs
Outputs of similar age
#907
of 274,613 outputs
Outputs of similar age from Annals of General Psychiatry
#1
of 1 outputs
Altmetric has tracked 20,023,934 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 470 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,613 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them