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OmpR and RcsB abolish temporal and spatial changes in expression of flhD in Escherichia coli Biofilm

Overview of attention for article published in BMC Microbiology, August 2013
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Title
OmpR and RcsB abolish temporal and spatial changes in expression of flhD in Escherichia coli Biofilm
Published in
BMC Microbiology, August 2013
DOI 10.1186/1471-2180-13-182
Pubmed ID
Authors

Priyankar Samanta, Emily R Clark, Katie Knutson, Shelley M Horne, Birgit M Prüß

Abstract

Biofilms are communities of bacteria that are characterized by specific phenotypes, including an increased resistance towards anti-microbials and the host immune system. This calls for the development of novel biofilm prevention and treatment options to combat infectious disease. In Escherichia coli, numerous global regulators have been implicated in the control of biofilm associated cell surface organelles. These include the flagellar regulator FlhD/FlhC, the osmoregulator EnvZ/OmpR, and the colanic acid activator RcsCDB. Using flow cell technology and fluorescence microscopy, we determined the temporal expression from flhD::gfp, ompR::gfp, and rcsB::gfp in E. coli biofilm, as well as the impact of the negative regulation of flhD by OmpR and RcsB. Spatial gene expression was investigated from flhD::gfp.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 24%
Researcher 10 22%
Student > Bachelor 5 11%
Student > Master 5 11%
Librarian 1 2%
Other 2 4%
Unknown 12 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 30%
Biochemistry, Genetics and Molecular Biology 7 15%
Immunology and Microbiology 3 7%
Environmental Science 2 4%
Nursing and Health Professions 1 2%
Other 5 11%
Unknown 14 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 August 2013.
All research outputs
#20,196,821
of 22,715,151 outputs
Outputs from BMC Microbiology
#2,674
of 3,171 outputs
Outputs of similar age
#174,098
of 198,117 outputs
Outputs of similar age from BMC Microbiology
#21
of 25 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,171 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,117 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.