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Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

Overview of attention for article published in Arthritis Research & Therapy, August 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

Mentioned by

news
1 news outlet

Citations

dimensions_citation
105 Dimensions

Readers on

mendeley
65 Mendeley
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Title
Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus
Published in
Arthritis Research & Therapy, August 2013
DOI 10.1186/ar4264
Pubmed ID
Authors

Jonatan Leffler, Birgitta Gullstrand, Andreas Jönsen, Jan-Åke Nilsson, Myriam Martin, Anna M Blom, Anders A Bengtsson

Abstract

The ability to degrade neutrophil extracellular traps (NETs) is reduced in a subset of patients with systemic lupus erythematosus (SLE). NETs consist of chromatin covered with antimicrobial enzymes and are normally degraded by DNase-I, an enzyme which is known to have reduced activity in SLE. Decreased ability to degrade NETs is associated with disease activity. In the current study we investigated how the ability of serum from SLE patients to degrade NETs varies during the course of SLE as well as what impact this may have for the clinical phenotype of SLE.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Poland 1 2%
Germany 1 2%
Brazil 1 2%
Unknown 61 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 22%
Student > Master 12 18%
Researcher 11 17%
Student > Bachelor 4 6%
Other 4 6%
Other 7 11%
Unknown 13 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 25%
Immunology and Microbiology 12 18%
Medicine and Dentistry 12 18%
Biochemistry, Genetics and Molecular Biology 4 6%
Psychology 3 5%
Other 3 5%
Unknown 15 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2013.
All research outputs
#4,836,164
of 25,374,917 outputs
Outputs from Arthritis Research & Therapy
#1,028
of 3,381 outputs
Outputs of similar age
#38,982
of 207,928 outputs
Outputs of similar age from Arthritis Research & Therapy
#13
of 51 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,928 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.