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Germline and somatic JAK2 mutations and susceptibility to chronic myeloproliferative neoplasms

Overview of attention for article published in Genome Medicine, May 2009
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)

Mentioned by

blogs
1 blog

Citations

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7 Dimensions

Readers on

mendeley
23 Mendeley
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Title
Germline and somatic JAK2 mutations and susceptibility to chronic myeloproliferative neoplasms
Published in
Genome Medicine, May 2009
DOI 10.1186/gm55
Pubmed ID
Authors

Lynn R Goldin, Magnus Björkholm, Sigurdur Y Kristinsson, Jan Samuelsson, Ola Landgren

Abstract

Myeloproliferative neoplasms (MPNs) are a group of closely related stem-cell-derived clonal proliferative diseases. Most cases are sporadic but first-degree relatives of MPN patients have a five- to seven-fold increased risk for developing an MPN. The tumors of most patients carry a mutation in the Janus kinase 2 gene (JAK2(V617F)). Recently, three groups have described a strong association of JAK2 germline polymorphisms with MPN in patients positive for JAK2(V617F). The somatic mutation occurs primarily on one particular germline JAK2 haplotype, which may account for as much as 50% of the risk to first-degree relatives. This finding provides new directions for unraveling the pathogenesis of MPN.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 26%
Student > Master 4 17%
Researcher 3 13%
Student > Bachelor 1 4%
Professor 1 4%
Other 4 17%
Unknown 4 17%
Readers by discipline Count As %
Medicine and Dentistry 7 30%
Agricultural and Biological Sciences 6 26%
Biochemistry, Genetics and Molecular Biology 3 13%
Business, Management and Accounting 1 4%
Immunology and Microbiology 1 4%
Other 1 4%
Unknown 4 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2013.
All research outputs
#5,861,869
of 22,716,996 outputs
Outputs from Genome Medicine
#998
of 1,435 outputs
Outputs of similar age
#32,415
of 113,970 outputs
Outputs of similar age from Genome Medicine
#2
of 4 outputs
Altmetric has tracked 22,716,996 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,435 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,970 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.