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Body mass index in girls with idiopathic central precocious puberty during and after treatment with GnRH analogues

Overview of attention for article published in International Journal of Pediatric Endocrinology, August 2016
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Title
Body mass index in girls with idiopathic central precocious puberty during and after treatment with GnRH analogues
Published in
International Journal of Pediatric Endocrinology, August 2016
DOI 10.1186/s13633-016-0033-7
Pubmed ID
Authors

A. J. Arcari, M. G. Gryngarten, A. V. Freire, M. G. Ballerini, M. G. Ropelato, I. Bergadá, M. E. Escobar

Abstract

In girls with Idiopathic Central Precocious Puberty (ICPP) concern has been raised by the potential impact of GnRH-analogues (GnRHa) treatment on body weight. We evaluated the effect of GnRHa on Body Mass Index (BMI) in girls with ICPP according to weight status at diagnosis. One hundred seventeen ICPP girls were divided according to pretreatment weight status in: normal weight (NW), overweight (OW) and obese (OB). BMI at one and two years of treatment was assessed. BMI-SDS of 60 patients who reached adult height (AH) was compared to that of 33 ICPP untreated girls. NW girls significantly increased their baseline BMI-SDS at 1 and 2 years of treatment. OW girls only had a significant increment at one year of treatment while OB girls showed no BMI-SDS change. Patients evaluated at AH (at least four years after GnRHa withdrawal) showed a significant decrease on BMI compared to baseline and a significantly lower BMI than the untreated group. In ICPP girls the BMI increase under GnRHa was inversely related to the pretreatment weight status. In the long term follow-up, no detrimental effect of GnRHa on body weight was observed. BMI-SDS was lower in treated than in untreated girls.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 15%
Other 1 5%
Student > Bachelor 1 5%
Unspecified 1 5%
Student > Ph. D. Student 1 5%
Other 3 15%
Unknown 10 50%
Readers by discipline Count As %
Medicine and Dentistry 8 40%
Biochemistry, Genetics and Molecular Biology 1 5%
Unspecified 1 5%
Unknown 10 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2017.
All research outputs
#16,722,190
of 25,374,917 outputs
Outputs from International Journal of Pediatric Endocrinology
#89
of 137 outputs
Outputs of similar age
#242,849
of 381,572 outputs
Outputs of similar age from International Journal of Pediatric Endocrinology
#1
of 2 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 137 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.6. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 381,572 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them